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  1. Original article

    Clinicopathologic features and treatment efficacy of Chinese patients with BRAF-mutated metastatic colorectal cancer: a retrospective observational study

    The prognostic role of the V600E mutation of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) in metastatic colorectal cancer (mCRC) is well established, but the therapeutic regimen targeting this disease is...

    Xicheng Wang, Qing Wei, Jing Gao, Jian Li, Jie Li, Jifang Gong, Yanyan Li and Lin Shen

    Chinese Journal of Cancer 2017 36:81

    Published on: 16 October 2017

  2. Original article

    Pathologic response after preoperative therapy predicts prognosis of Chinese colorectal cancer patients with liver metastases

    Pathologic response is evaluated according to the extent of tumor regression and is used to estimate the efficacy of preoperative treatment. Several studies have reported the association between the pathologic...

    Yun Wang, Yun-Fei Yuan, Hao-Cheng Lin, Bin-Kui Li, Feng-Hua Wang, Zhi-Qiang Wang, Pei-Rong Ding, Gong Chen, Xiao-Jun Wu, Zhen-Hai Lu, Zhi-Zhong Pan, De-Sen Wan, Peng Sun, Shu-Mei Yan, Rui-Hua Xu and Yu-Hong Li

    Chinese Journal of Cancer 2017 36:78

    Published on: 2 October 2017

  3. Original article

    Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer

    Reduced expression of tripartite motif-containing 3 (TRIM3) has been reported to be involved in the pathogenesis of human glioblastoma. In our previous research, we found that TRIM3 expression was markedly reduce...

    Xu-Qiong Huang, Xiao-Fei Zhang, Jin-Hua Xia, Jie Chao, Qiu-Zhong Pan, Jing-Jing Zhao, Zi-Qi Zhou, Chang-Long Chen, Yan Tang, De-Sheng Weng, Jian-Hua Zhang and Jian-Chuan Xia

    Chinese Journal of Cancer 2017 36:77

    Published on: 26 September 2017

  4. Original article

    Effects of dosimetric inadequacy on local control and toxicities in the patients with T4 nasopharyngeal carcinoma extending into the intracranial space and treated with intensity-modulated radiotherapy plus chemotherapy

    To protect neurological tissues, underdosing occurs in most cases of T4 nasopharyngeal carcinoma (NPC) with intracranial extension. In this study, we aimed to evaluate the effect of dosimetric inadequacy on lo...

    Fen Xue, Chao-Su Hu and Xia-Yun He

    Chinese Journal of Cancer 2017 36:76

    Published on: 20 September 2017

  5. Original article

    Prognostic value of systemic immune-inflammation index in patients with gastric cancer

    Inflammation-based indexes have been used to predict survival and recurrence in cancer patients. Systemic immune-inflammation index (SII) was reported to be associated with prognosis in some malignant tumors. ...

    Kang Wang, Feiyu Diao, Zhijun Ye, Xinhua Zhang, Ertao Zhai, Hui Ren, Tong Li, Hui Wu, Yulong He, Shirong Cai and Jianhui Chen

    Chinese Journal of Cancer 2017 36:75

    Published on: 12 September 2017

  6. Original article

    Efficacy and safety of controlled-release oxycodone/naloxone versus controlled-release oxycodone in Korean patients with cancer-related pain: a randomized controlled trial

    Controlled-release oxycodone/naloxone (OXN-CR) maintains the effect of opioid-induced analgesia through oxycodone while reducing the occurrence rate of opioid-induced constipation through naloxone. The present...

    Kyung-Hee Lee, Tae Won Kim, Jung-Hun Kang, Jin-Soo Kim, Jin-Seok Ahn, Sun-Young Kim, Hwan-Jung Yun, Young-Jun Eum, Sung Ae Koh, Min Kyoung Kim, Yong Sang Hong, Jeong Eun Kim and Gyeong-Won Lee

    Chinese Journal of Cancer 2017 36:74

    Published on: 11 September 2017

  7. Original article

    Medical expenditure for esophageal cancer in China: a 10-year multicenter retrospective survey (2002–2011)

    Esophageal cancer is associated with substantial disease burden in China, and data on the economic burden are fundamental for setting priorities in cancer interventions. The medical expenditure for the diagnos...

    Lan-Wei Guo, Hui-Yao Huang, Ju-Fang Shi, Li-Hong Lv, Ya-Na Bai, A-Yan Mao, Xian-Zhen Liao, Guo-Xiang Liu, Jian-Song Ren, Xiao-Jie Sun, Xin-Yu Zhu, Jin-Yi Zhou, Ji-Yong Gong, Qi Zhou, Lin Zhu, Yu-Qin Liu…

    Chinese Journal of Cancer 2017 36:73

    Published on: 7 September 2017

  8. Original article

    Potential factors associated with clinical stage of nasopharyngeal carcinoma at diagnosis: a case–control study

    In China, most patients with nasopharyngeal carcinoma (NPC) are diagnosed at a late stage and consequently have a poor prognosis. This study aimed to investigate potential factors associated with the clinical ...

    Jun-Ting Ren, Meng-Yu Li, Xiao-Wen Wang, Wen-Qiong Xue, Ze-Fang Ren and Wei-Hua Jia

    Chinese Journal of Cancer 2017 36:71

    Published on: 4 September 2017

  9. Editorial

    Awakening immunity against cancer: a 2017 primer for clinicians

    Cancer immunotherapy has finally joined the pillars of cancer treatment—surgery, radiation, chemotherapy, hormonal therapy, and targeted therapy—in improving cancer patient lives. In the last 5 years, the deve...

    Amit Jain, Qing Zhang and Han-Chong Toh

    Chinese Journal of Cancer 2017 36:67

    Published on: 20 August 2017

  10. Short report

    Estimates of cancer incidence and mortality in China, 2013

    Population-based cancer registration data are collected by the National Central Cancer Registry in China every year. Cancer incident cases and cancer deaths in 2013 were analyzed.

    Rongshou Zheng, Hongmei Zeng, Siwei Zhang and Wanqing Chen

    Chinese Journal of Cancer 2017 36:66

    Published on: 17 August 2017

  11. Original article

    Comparison of efficacy, safety, and quality of life between sorafenib and sunitinib as first-line therapy for Chinese patients with metastatic renal cell carcinoma

    Sorafenib and sunitinib are widely used as first-line targeted therapy for metastatic renal cell carcinoma (mRCC) in China. This study aimed to compare the efficacy, safety, and quality of life (QoL) in Chines...

    Wen Cai, Wen Kong, Baijun Dong, Jin Zhang, Yonghui Chen, Wei Xue, Yiran Huang, Lixin Zhou and Jiwei Huang

    Chinese Journal of Cancer 2017 36:64

    Published on: 8 August 2017

  12. Original article

    Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance to trametinib in colorectal cancer cells

    The mitogen-activated extracellular signal-regulated kinase 1/2 (MEK1/2) inhibitor trametinib has shown promising therapeutic effects on melanoma, but its efficacy on colorectal cancer (CRC) is limited. Synthe...

    Rong Geng, Xin Tan, Zhixiang Zuo, Jiangxue Wu, Zhizhong Pan, Wei Shi, Ranyi Liu, Chen Yao, Gaoyuan Wang, Jiaxin Lin, Lin Qiu, Wenlin Huang and Shuai Chen

    Chinese Journal of Cancer 2017 36:63

    Published on: 31 July 2017

  13. Original article

    Prognostic role of ABO blood type in patients with extranodal natural killer/T cell lymphoma, nasal type: a triple-center study

    The prognostic significance of ABO blood type for lymphoma is largely unknown. We evaluated the prognostic role of ABO blood type in patients with extranodal natural killer (NK)/T-cell lymphoma (ENKTL).

    Ya-Jun Li, Ping-Yong Yi, Ji-Wei Li, Xian-Ling Liu, Tian Tang, Pei-Ying Zhang and Wen-Qi Jiang

    Chinese Journal of Cancer 2017 36:62

    Published on: 31 July 2017

  14. Original article

    Prognostic value of programmed death-1, programmed death-ligand 1, programmed death-ligand 2 expression, and CD8(+) T cell density in primary tumors and metastatic lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma

    Anti-programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) immunotherapy has been proved to be effective on gastric cancer in ongoing clinical trials. However, the value of PD-L1 in predicting responses of...

    Yuan Gao, Su Li, Dazhi Xu, Shangxiang Chen, Yuchen Cai, Wenqi Jiang, Xinke Zhang, Jin Sun, Kefeng Wang, Boyang Chang, Fenghua Wang and Minghuang Hong

    Chinese Journal of Cancer 2017 36:61

    Published on: 29 July 2017

  15. Original article

    Transarterial chemoembolization combined with recombinant human adenovirus type 5 H101 prolongs overall survival of patients with intermediate to advanced hepatocellular carcinoma: a prognostic nomogram study

    Patients with intermediate to advanced hepatocellular carcinoma (HCC) are most commonly treated with transarterial chemoembolization (TACE). Previous studies showed that TACE combined with recombinant human ad...

    Chao-Bin He, Xiang-Ming Lao and Xiao-Jun Lin

    Chinese Journal of Cancer 2017 36:59

    Published on: 20 July 2017

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Chinese Journal of Cancer is affiliated to the Chinese Anti-Cancer Association and the US Chinese Anti-Cancer Association.