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  1. Editorial

    Cancer metastasis: issues and challenges

    Metastasis is the major cause of treatment failure in cancer patients and of cancer-related deaths. This editorial discusses how cancer metastasis may be better perceived and controlled. Based on big-data anal...

    Chao-Nan Qian, Yan Mei and Jian Zhang

    Chinese Journal of Cancer 2017 36:38

    Published on: 3 April 2017

  2. Original article

    Down-regulation of E-cadherin enhances prostate cancer chemoresistance via Notch signaling

    The chemoresistance of prostate cancer (PCa) is invariably associated with the aggressiveness and metastasis of this disease. New emerging evidence indicates that the epithelial-to-mesenchymal transition (EMT)...

    Wenchu Wang, Lihui Wang, Atsushi Mizokami, Junlin Shi, Chunlin Zou, Jinlu Dai, Evan T. Keller, Yi Lu and Jian Zhang

    Chinese Journal of Cancer 2017 36:35

    Published on: 29 March 2017

  3. Original article

    Clinical treatment considerations in the intensity-modulated radiotherapy era for patients with N0-category nasopharyngeal carcinoma and enlarged neck lymph nodes

    Nasopharyngeal carcinoma (NPC) shows a high proportion of lymph node metastasis, and treatment guidelines have been developed for positive nodes. However, no irradiation guidelines have been proposed for patie...

    Hao Peng, Lei Chen, Rui Guo, Yuan Zhang, Wen-Fei Li, Yan-Ping Mao, Ying Sun, Fan Zhang, Li-Zhi Liu, Li Tian and Jun Ma

    Chinese Journal of Cancer 2017 36:32

    Published on: 24 March 2017

  4. Original article

    Left jackknife position: a novel position for laparoscopic hepatectomy

    Laparoscopic hepatectomy for hepatocellular carcinoma (HCC) located in segment VI, VII, or VIII of the liver is usually difficult because of poor operative exposure, due to the unique anatomical structure. In ...

    Jian-Cong Chen, Rong-Xin Zhang, Min-Shan Chen, Li Xu, Jin-Bin Chen, Ke-Li Yang, Yao-Jun Zhang and Zhong-Guo Zhou

    Chinese Journal of Cancer 2017 36:31

    Published on: 20 March 2017

  5. Review

    Immune mediators in the tumor microenvironment of prostate cancer

    Prostate cancer tissue is composed of both cancer cells and host cells. The milieu of host components that compose the tumor is termed the tumor microenvironment (TME). Host cells can be those derived from the...

    Jinlu Dai, Yi Lu, Hernan Roca, Jill M. Keller, Jian Zhang, Laurie K. McCauley and Evan T. Keller

    Chinese Journal of Cancer 2017 36:29

    Published on: 14 March 2017

  6. Original article

    Weekly taxane–anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally advanced breast cancer: a randomized controlled trial

    Extensive studies have confirmed the efficacy of taxanes in combination with anthracycline-based chemotherapy on breast cancer. However, few studies have assessed the efficacy of weekly taxane–anthracycline re...

    Qiu-Wen Tan, Ting Luo, Hong Zheng, Ting-Lun Tian, Ping He, Jie Chen, He-Lin Zeng and Qing Lv

    Chinese Journal of Cancer 2017 36:27

    Published on: 7 March 2017

  7. Original article

    Radiotherapy with neoadjuvant chemotherapy versus concurrent chemoradiotherapy for ascending-type nasopharyngeal carcinoma: a retrospective comparison of toxicity and prognosis

    In the era of intensity-modulated radiotherapy (IMRT), the role of neoadjuvant chemotherapy (NACT) in treating ascending-type nasopharyngeal carcinoma (NPC) is under-evaluated. This study was to compare the ef...

    Ji-Jin Yao, Xiao-Li Yu, Fan Zhang, Wang-Jian Zhang, Guan-Qun Zhou, Ling-Long Tang, Yan-Ping Mao, Lei Chen, Jun Ma and Ying Sun

    Chinese Journal of Cancer 2017 36:26

    Published on: 6 March 2017

  8. Original article

    Californium-252 neutron brachytherapy combined with external pelvic radiotherapy plus concurrent chemotherapy for cervical cancer: a retrospective clinical study

    Cervical cancer is the sixth most common cancer in Chinese women. A standard treatment modality for cervical cancer is the combination of surgery, chemotherapy, external-beam radiotherapy and intracavitary bra...

    Shen Qian, Ling Ye, Yun-Hong Tian, Li-Gen Wang, Zuo-Ping Huang, Feng Li, Bing Hou, Ni Song, Juan Chen, Ying Liu, Xiao Liu and Tao Zhou

    Chinese Journal of Cancer 2017 36:24

    Published on: 28 February 2017

  9. Original article

    Prognostic value of alcohol consumption and some other dietary habits for survival in a cohort of Chinese men with lung cancer

    Alcohol consumption and some other dietary habits are thought to be associated with lung cancer incidence. However, the effects of these habits on lung cancer prognosis have been studied rarely. The purpose of...

    Wentao Li, Lap Ah Tse, Joseph S. K. Au, Kai Shing Yu, Feng Wang and Ignatius Tak-sun Yu

    Chinese Journal of Cancer 2017 36:21

    Published on: 10 February 2017

  10. Original article

    Proportion and clinical features of never-smokers with non-small cell lung cancer

    The proportion of never-smokers with non-small cell lung cancer (NSCLC) is increasing, but that in Korea has not been well addressed in a large population. We aimed to evaluate the proportion and clinical feat...

    Jaeyoung Cho, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee, Sang-Min Lee, Dong-Wan Kim, Jae-Joon Yim, Young Tae Kim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han and Young Sik Park

    Chinese Journal of Cancer 2017 36:20

    Published on: 8 February 2017

  11. Original article

    Id4 promotes cell proliferation in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is a common malignant tumor in the world, especially in China. As a member of the inhibitor of differentiation (Id) family, Id4 has been reported to function in many cancer types, b...

    Yang Zhang, Li-Xing Zhang, Xiao-Qin Liu, Fang-Yu Zhao, Chao Ge, Tao-Yang Chen, Ming Yao and Jin-Jun Li

    Chinese Journal of Cancer 2017 36:19

    Published on: 1 February 2017

  12. Review

    Metformin targets multiple signaling pathways in cancer

    Metformin, an inexpensive and well-tolerated oral agent commonly used in the first-line treatment of type 2 diabetes, has become the focus of intense research as a candidate anticancer agent. Here, we discuss ...

    Yong Lei, Yanhua Yi, Yang Liu, Xia Liu, Evan T. Keller, Chao-Nan Qian, Jian Zhang and Yi Lu

    Chinese Journal of Cancer 2017 36:17

    Published on: 26 January 2017

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