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  1. Original article

    Clinical treatment considerations in the intensity-modulated radiotherapy era for patients with N0-category nasopharyngeal carcinoma and enlarged neck lymph nodes

    Nasopharyngeal carcinoma (NPC) shows a high proportion of lymph node metastasis, and treatment guidelines have been developed for positive nodes. However, no irradiation guidelines have been proposed for patie...

    Hao Peng, Lei Chen, Rui Guo, Yuan Zhang, Wen-Fei Li, Yan-Ping Mao, Ying Sun, Fan Zhang, Li-Zhi Liu, Li Tian and Jun Ma

    Chinese Journal of Cancer 2017 36:32

    Published on: 24 March 2017

  2. Original article

    Left jackknife position: a novel position for laparoscopic hepatectomy

    Laparoscopic hepatectomy for hepatocellular carcinoma (HCC) located in segment VI, VII, or VIII of the liver is usually difficult because of poor operative exposure, due to the unique anatomical structure. In ...

    Jian-Cong Chen, Rong-Xin Zhang, Min-Shan Chen, Li Xu, Jin-Bin Chen, Ke-Li Yang, Yao-Jun Zhang and Zhong-Guo Zhou

    Chinese Journal of Cancer 2017 36:31

    Published on: 20 March 2017

  3. Review

    Immune mediators in the tumor microenvironment of prostate cancer

    Prostate cancer tissue is composed of both cancer cells and host cells. The milieu of host components that compose the tumor is termed the tumor microenvironment (TME). Host cells can be those derived from the...

    Jinlu Dai, Yi Lu, Hernan Roca, Jill M. Keller, Jian Zhang, Laurie K. McCauley and Evan T. Keller

    Chinese Journal of Cancer 2017 36:29

    Published on: 14 March 2017

  4. Original article

    Weekly taxane–anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally advanced breast cancer: a randomized controlled trial

    Extensive studies have confirmed the efficacy of taxanes in combination with anthracycline-based chemotherapy on breast cancer. However, few studies have assessed the efficacy of weekly taxane–anthracycline re...

    Qiu-Wen Tan, Ting Luo, Hong Zheng, Ting-Lun Tian, Ping He, Jie Chen, He-Lin Zeng and Qing Lv

    Chinese Journal of Cancer 2017 36:27

    Published on: 7 March 2017

  5. Original article

    Radiotherapy with neoadjuvant chemotherapy versus concurrent chemoradiotherapy for ascending-type nasopharyngeal carcinoma: a retrospective comparison of toxicity and prognosis

    In the era of intensity-modulated radiotherapy (IMRT), the role of neoadjuvant chemotherapy (NACT) in treating ascending-type nasopharyngeal carcinoma (NPC) is under-evaluated. This study was to compare the ef...

    Ji-Jin Yao, Xiao-Li Yu, Fan Zhang, Wang-Jian Zhang, Guan-Qun Zhou, Ling-Long Tang, Yan-Ping Mao, Lei Chen, Jun Ma and Ying Sun

    Chinese Journal of Cancer 2017 36:26

    Published on: 6 March 2017

  6. Original article

    Californium-252 neutron brachytherapy combined with external pelvic radiotherapy plus concurrent chemotherapy for cervical cancer: a retrospective clinical study

    Cervical cancer is the sixth most common cancer in Chinese women. A standard treatment modality for cervical cancer is the combination of surgery, chemotherapy, external-beam radiotherapy and intracavitary bra...

    Shen Qian, Ling Ye, Yun-Hong Tian, Li-Gen Wang, Zuo-Ping Huang, Feng Li, Bing Hou, Ni Song, Juan Chen, Ying Liu, Xiao Liu and Tao Zhou

    Chinese Journal of Cancer 2017 36:24

    Published on: 28 February 2017

  7. Original article

    Prognostic value of alcohol consumption and some other dietary habits for survival in a cohort of Chinese men with lung cancer

    Alcohol consumption and some other dietary habits are thought to be associated with lung cancer incidence. However, the effects of these habits on lung cancer prognosis have been studied rarely. The purpose of...

    Wentao Li, Lap Ah Tse, Joseph S. K. Au, Kai Shing Yu, Feng Wang and Ignatius Tak-sun Yu

    Chinese Journal of Cancer 2017 36:21

    Published on: 10 February 2017

  8. Original article

    Proportion and clinical features of never-smokers with non-small cell lung cancer

    The proportion of never-smokers with non-small cell lung cancer (NSCLC) is increasing, but that in Korea has not been well addressed in a large population. We aimed to evaluate the proportion and clinical feat...

    Jaeyoung Cho, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee, Sang-Min Lee, Dong-Wan Kim, Jae-Joon Yim, Young Tae Kim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han and Young Sik Park

    Chinese Journal of Cancer 2017 36:20

    Published on: 8 February 2017

  9. Original article

    Id4 promotes cell proliferation in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is a common malignant tumor in the world, especially in China. As a member of the inhibitor of differentiation (Id) family, Id4 has been reported to function in many cancer types, b...

    Yang Zhang, Li-Xing Zhang, Xiao-Qin Liu, Fang-Yu Zhao, Chao Ge, Tao-Yang Chen, Ming Yao and Jin-Jun Li

    Chinese Journal of Cancer 2017 36:19

    Published on: 1 February 2017

  10. Review

    Metformin targets multiple signaling pathways in cancer

    Metformin, an inexpensive and well-tolerated oral agent commonly used in the first-line treatment of type 2 diabetes, has become the focus of intense research as a candidate anticancer agent. Here, we discuss ...

    Yong Lei, Yanhua Yi, Yang Liu, Xia Liu, Evan T. Keller, Chao-Nan Qian, Jian Zhang and Yi Lu

    Chinese Journal of Cancer 2017 36:17

    Published on: 26 January 2017

  11. Original article

    Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study

    Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related death, and new prognostic biomarkers are urgently needed. Apoptosis-stimulating P53-binding protein 1 (ASPP1) and 2 (ASPP2) have b...

    Xiao-Feng Xie, Qing Yang, Jun Chi, Xian-Zi Yang, Hui-Yun Wang and Guo-Liang Xu

    Chinese Journal of Cancer 2017 36:15

    Published on: 19 January 2017

  12. Original article

    Microwave ablation is as effective as radiofrequency ablation for very-early-stage hepatocellular carcinoma

    Percutaneous radiofrequency ablation (RFA) is a first-line treatment for very-early-stage hepatocellular carcinoma (HCC), whereas the efficacy of percutaneous microwave ablation (MWA) for very-early-stage HCC ...

    Yun Xu, Qiang Shen, Neng Wang, Pan-Pan Wu, Bin Huang, Ming Kuang and Guo-Jun Qian

    Chinese Journal of Cancer 2017 36:14

    Published on: 19 January 2017

  13. News and Views

    The most important questions in cancer research and clinical oncology

    Specific research foci: (1) Mouse models of gamma-herpes virus-68 (γHV-68) and polyomavirus (PyV) infections during neonatal versus adult life. (2) For human papilloma virus (HPV)-positive oropharyngeal carcin...

    Joseph T. S. Wee and Sharon Shuxian Poh

    Chinese Journal of Cancer 2017 36:13

    Published on: 16 January 2017

  14. Original article

    Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients

    Chemotherapy toxicity is a serious problem from which non-small cell lung cancer (NSCLC) patients suffer. The mismatch repair (MMR) system is associated with platinum-based chemotherapy toxicity in NSCLC patie...

    Jun-Yan Liu, Chen-Yue Qian, Yuan-Feng Gao, Juan Chen, Hong-Hao Zhou and Ji-Ye Yin

    Chinese Journal of Cancer 2017 36:12

    Published on: 16 January 2017

  15. Original article

    The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells

    Ankyrin repeat and SOCS box protein 3 (ASB3) is a member of ASB family and contains ankyrin repeat sequence and SOCS box domain. Previous studies indicated that it mediates the ubiquitination and degradation o...

    Wu-Ying Du, Zhen-Hai Lu, Wen Ye, Xiang Fu, Yi Zhou, Chun-Mei Kuang, Jiang-Xue Wu, Zhi-Zhong Pan, Shuai Chen, Ran-Yi Liu and Wen-Lin Huang

    Chinese Journal of Cancer 2017 36:11

    Published on: 14 January 2017

  16. Original article

    The efficacy of fluoropyrimidine-based adjuvant chemotherapy on biliary tract cancer after R0 resection

    The optimal treatment strategy for biliary tract cancer (BTC) after curative-intent resection remains controversial. The purpose of this study was to evaluate the efficacy of fluoropyrimidine-based adjuvant ch...

    Young Saing Kim, Chi-Young Jeong, Haa-Na Song, Tae Hyo Kim, Hong Jun Kim, Young-Joon Lee and Soon Chan Hong

    Chinese Journal of Cancer 2017 36:9

    Published on: 13 January 2017

  17. Case report

    Is there still a role for cytotoxic chemotherapy after targeted therapy and immunotherapy in metastatic melanoma? A case report and literature review

    Metastatic melanoma has long been considered to have a very poor prognosis and to be chemo-resistant. However, a subgroup of patients with metastatic melanoma presents remarkable responses to chemotherapeutic ...

    Aurélien Simon, Hampig Raphael Kourie and Joseph Kerger

    Chinese Journal of Cancer 2017 36:10

    Published on: 13 January 2017

  18. Original article

    Concurrent chemoradiotherapy combined with enteral nutrition support: a radical treatment strategy for esophageal squamous cell carcinoma patients with malignant fistulae

    Concurrent chemoradiotherapy (CCRT) significantly increases the survival rate of esophageal squamous cell carcinoma (ESCC) patients with malignant fistulae. Recent clinical evidence has shown the benefits of e...

    Li Ma, Guang-Yu Luo, Yu-Feng Ren, Bo Qiu, Hong Yang, Chun-Xia Xie, Song-Ran Liu, Shi-Liang Liu, Zhao-Lin Chen, Qun Li, Jian-Hua Fu, Meng-Zhong Liu, Yong-Hong Hu, Wen-Feng Ye and Hui Liu

    Chinese Journal of Cancer 2017 36:8

    Published on: 11 January 2017

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